Evaluation of lymphotoxin-alpha in pterygium and diagnostic value in active and inactive pterygium states

Autor: Guoli Lan, Xie Fang, Yanlin Zhong, Shunrong Luo, Xianwen Xiao, Zhiwen Xie, Lianghuan Luo, Yiqiu Zhang, Hanqiao Li, Yuan Lin, Huping Wu
Jazyk: angličtina
Rok vydání: 2024
Předmět:
Zdroj: Scientific Reports, Vol 14, Iss 1, Pp 1-10 (2024)
Druh dokumentu: article
ISSN: 2045-2322
DOI: 10.1038/s41598-024-52382-z
Popis: Abstract To explore the correlation between tear LT-a, pterygium status, and dry eye indicators. We established a diagnostic model to evaluate active pterygium. A retrospective study was conducted between June 2021 and June 2023 on 172 patients, comprising 108 men and 64 women. The study analyzed LT-a and various ocular parameters in all participants. The data was collected using Excel software and analyzed using SPSS 25.0 statistical software and Medcalc. We made a nomogram diagnostic model to different diagnosed the state of pterygium. This study found that pterygium has progressive eye surface damage during the active state. There was no significant difference in dry eye indicators between the two groups. However, the concentration of LT-a in the active group was significantly lower than that in the inactive group (P
Databáze: Directory of Open Access Journals
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