| Autor: |
Nizamettin Guzel, Emrah Sayit, Osman Aynaci, Servet Kerimoglu, Esin Yulug, Murat Topbas |
| Jazyk: |
English<br />Portuguese |
| Rok vydání: |
2017 |
| Předmět: |
|
| Zdroj: |
Acta Ortopédica Brasileira, Vol 25, Iss 3, Pp 95-98 (2017) |
| Druh dokumentu: |
article |
| ISSN: |
1413-7852 |
| DOI: |
10.1590/1413-785220172503156966 |
| Popis: |
ABSTRACT OBJECTIVES: Ginkgo biloba extract (EGb 761) is a plant extract obtained from the leaves of the G. biloba tree. The aim of this study was to assess the histological and radiological effects of G. biloba extract on fracture healing in an experimental fracture model using rat femurs. METHODS: Forty-eight female Sprague-Dawley rats (weight: 195-252 g; age: 20 weeks) were used in the study. The rats were randomly divided into six groups (n=8). A transverse fracture was made in the middle of the right femur of each rat and fixed with a Kirschner wire. The G. biloba groups received 60 mg/kg oral G. biloba extract once daily. No medication was given to the control groups. On days 7, 21 and 35, both sets of femurs were evaluated radiologically and histopathologically. RESULTS: Histological evaluation revealed that the G. biloba groups had significant differences at 21 and 35 days (p |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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