An Arg/Ala-rich helix in the N-terminal region of M. tuberculosis FtsQ is a potential membrane anchor of the Z-ring

Autor: Sean T. Smrt, Cristian A. Escobar, Souvik Dey, Timothy A. Cross, Huan-Xiang Zhou
Jazyk: angličtina
Rok vydání: 2023
Předmět:
Zdroj: Communications Biology, Vol 6, Iss 1, Pp 1-11 (2023)
Druh dokumentu: article
ISSN: 2399-3642
DOI: 10.1038/s42003-023-04686-5
Popis: The disordered cytoplasmic region of Mtb FtsQ can interact with three partners – the upstream acidic residues in solution, the inner membrane surface, and the GTPase domain of FtsZ – suggesting its role in cell division and as a drug target.
Databáze: Directory of Open Access Journals