Risk of chronic liver disease in post-menopausal women due to body mass index, alcohol and their interaction: a prospective nested cohort study within the United Kingdom Collaborative Trial of Ovarian Cancer Screening (UKCTOCS)

Autor: Paul M Trembling, Sophia Apostolidou, Aleksandra Gentry-Maharaj, Julie Parkes, Andy Ryan, Sudeep Tanwar, Matthew Burnell, Ian Jacobs, Usha Menon, William M. Rosenberg
Jazyk: angličtina
Rok vydání: 2017
Předmět:
Zdroj: BMC Public Health, Vol 17, Iss 1, Pp 1-9 (2017)
Druh dokumentu: article
ISSN: 1471-2458
DOI: 10.1186/s12889-017-4518-y
Popis: Abstract Background We investigated the risk of chronic liver disease (CLD) due to alcohol consumption and body mass index (BMI) and the effects of their interaction in a prospective cohort study of women recruited to the UKCTOCS trial. Methods 95,126 post-menopausal women without documented CLD were stratified into 12 groups defined by combinations of BMI (normal, overweight, obese) and alcohol consumption (none,
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