Automatic fovea detection and choroid segmentation for choroidal thickness assessment in optical coherence tomography
| Autor: | Chen Yu Lin, Hung Ju Chen, Yi Kit Chan, Wei Ping Hsia, Yu Len Huang, Chia Jen Chang |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2024 |
| Předmět: | |
| Zdroj: | International Journal of Ophthalmology, Vol 17, Iss 10, Pp 1763-1771 (2024) |
| Druh dokumentu: | article |
| ISSN: | 2222-3959 2227-4898 |
| DOI: | 10.18240/ijo.2024.10.01 |
| Popis: | AIM: To develop an automated model for subfoveal choroidal thickness (SFCT) detection in optical coherence tomography (OCT) images, addressing manual fovea location and choroidal contour challenges. METHODS: Two procedures were proposed: defining the fovea and segmenting the choroid. Fovea localization from B-scan OCT image sequence with three-dimensional reconstruction (LocBscan-3D) predicted fovea location using central foveal depression features, and fovea localization from two-dimensional en-face OCT (LocEN-2D) used a mask region-based convolutional neural network (Mask R-CNN) model for optic disc detection, and determined the fovea location based on optic disc relative position. Choroid segmentation also employed Mask R-CNN. RESULTS: For 53 eyes in 28 healthy subjects, LocBscan-3D's mean difference between manual and predicted fovea locations was 170.0 μm, LocEN-2D yielded 675.9 μm. LocEN-2D performed better in non-high myopia group (P=0.02). SFCT measurements from Mask R-CNN aligned with manual values. CONCLUSION: Our models accurately predict SFCT in OCT images. LocBscan-3D excels in precise fovea localization even with high myopia. LocEN-2D shows high detection rates but lower accuracy especially in the high myopia group. Combining both models offers a robust SFCT assessment approach, promising efficiency and accuracy for large-scale studies and clinical use. |
| Databáze: | Directory of Open Access Journals |
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