Growth Hormone and the Auditory Pathway: Neuromodulation and Neuroregeneration

Autor:	Joaquín Guerra Gómez, Jesús Devesa
Jazyk:	angličtina
Rok vydání:	2021
Předmět:	growth hormone IGF-I central auditory processing hearing impairment hereditary hearing loss GH deficiency Biology (General) QH301-705.5 Chemistry QD1-999
Zdroj:	International Journal of Molecular Sciences, Vol 22, Iss 6, p 2829 (2021)
Druh dokumentu:	article
ISSN:	1422-0067 1661-6596
DOI:	10.3390/ijms22062829
Popis:	Growth hormone (GH) plays an important role in auditory development during the embryonic stage. Exogenous agents such as sound, noise, drugs or trauma, can induce the release of this hormone to perform a protective function and stimulate other mediators that protect the auditory pathway. In addition, GH deficiency conditions hearing loss or central auditory processing disorders. There are promising animal studies that reflect a possible regenerative role when exogenous GH is used in hearing impairments, demonstrated in in vivo and in vitro studies, and also, even a few studies show beneficial effects in humans presented and substantiated in the main text, although they should not exaggerate the main conclusions.
Databáze:	Directory of Open Access Journals
Externí odkaz:	https://doaj.org/article/8a1043685cdb4d8288b219abcb19bb8b Zobrazit plný text záznamu View record in DOAJ Plný text ve formátu PDF