Autor: |
Ismayil Ahmet, Edward Spangler, Barbara Shukitt-Hale, Magdalena Juhaszova, Steven J Sollott, James A Joseph, Donald K Ingram, Mark Talan |
Jazyk: |
angličtina |
Rok vydání: |
2009 |
Předmět: |
|
Zdroj: |
PLoS ONE, Vol 4, Iss 6, p e5954 (2009) |
Druh dokumentu: |
article |
ISSN: |
1932-6203 |
DOI: |
10.1371/journal.pone.0005954 |
Popis: |
OBJECTIVES:to assess the cardioprotective properties of a blueberry enriched diet (BD). BACKGROUND:Reactive oxygen species (ROS) play a major role in ischemia-related myocardial injury. The attempts to use synthetic antioxidants to block the detrimental effects of ROS have produced mixed or negative results precipitating the interest in natural products. Blueberries are readily available product with the highest antioxidant capacity among fruits and vegetables. METHODS AND RESULTS:Following 3-mo of BD or a regular control diet (CD), the threshold for mitochondrial permeability transition (t(MPT)) was measured in isolated cardiomyocytes obtained from young male Fischer-344 rats. Compared to CD, BD resulted in a 24% increase (p |
Databáze: |
Directory of Open Access Journals |
Externí odkaz: |
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