Impact of diabetes and early revascularization on the need for late and repeat procedures

Autor: Ady Orbach, David A. Halon, Ronen Jaffe, Ronen Rubinshtein, Basheer Karkabi, Moshe Y. Flugelman, Barak Zafrir
Jazyk: angličtina
Rok vydání: 2018
Předmět:
Zdroj: Cardiovascular Diabetology, Vol 17, Iss 1, Pp 1-9 (2018)
Druh dokumentu: article
ISSN: 1475-2840
DOI: 10.1186/s12933-018-0669-0
Popis: Abstract Background Coronary artery disease often progresses more rapidly in diabetics, but the integrated impact of diabetes and early revascularization status on late or repeat revascularization in the contemporary era is less clear. Methods Coronary angiography was performed in 12,420 patients between the years 2000–2015 and early revascularization status [none, percutaneous coronary intervention (PCI) or bypass surgery (CABG)] was determined. Subsequent revascularization procedures were recorded over a median follow-up of 67 months and its relation to diabetic and baseline revascularization status was studied. Results Early revascularization status was none in 5391, PCI in 5682 and CABG in 1347 patients. Late revascularization rates were 10, 26 and 11.1% respectively. Diabetes was present in 37%; a stepwise relationship of diabetic status with late revascularization was observed: no diabetes (reference) 14.4%, non-insulin treated diabetes 21% (adjusted HR 1.35, 95% CI 1.23–1.49, p
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