Lenacapavir with Fostemsavir in a Multidrug-Resistant HIV-Infected Hemodialysis Patient

Autor:	Ferdinand Bigirimana, Sigi Van den Wijngaert, Christelle Fosso, Karolien Stoffels, Charlotte Martin, Evelyne Maillart, Philippe Clevenbergh
Jazyk:	angličtina
Rok vydání:	2023
Předmět:	Infectious and parasitic diseases RC109-216
Zdroj:	Case Reports in Infectious Diseases, Vol 2023 (2023)
Druh dokumentu:	article
ISSN:	2090-6633
DOI:	10.1155/2023/8865265
Popis:	We report a hemodialysis MDR HIV-infected patient switched to fostemsavir with lenacapavir plus lamivudine for more than a year. She maintained a suppressed viral replication and did not present any clinical or biological drug-related side effects. The combination of lenacapavir plus fostemsavir looks promising in terms of safety and efficacy even in patients with end-stage renal disease awaiting renal transplant. Both drugs are first in class ARVs so that there is no cross resistance with previous drugs, maintaining their efficacy against MDR HIV.
Databáze:	Directory of Open Access Journals
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