Cystoid Macular Edema following Treatment with Nanoparticle Albumin-Bound Paclitaxel and Atezolizumab for Metastatic Breast Cancer

Autor: Hiroaki Yamane, Tomoko Itagaki, Keiko Kajitani, Yuji Koura, Yoshiharu Kawabuchi, Masahiro Ohara
Jazyk: angličtina
Rok vydání: 2023
Předmět:
Zdroj: Case Reports in Oncology, Vol 16, Iss 1, Pp 1121-1128 (2023)
Druh dokumentu: article
ISSN: 1662-6575
DOI: 10.1159/000533999
Popis: Cystoid macular edema (CME) is a rare side effect associated with chemotherapy. Although the development of CME has been reported to occur following treatment with taxane drugs, such as nanoparticle albumin-bound paclitaxel (Nab-PTX), the occurrence of CME with treatment with atezolizumab has not yet been reported. Here, we report the case of a 49-year-old woman who developed CME 19 months into chemotherapy with Nab-PTX and atezolizumab. Improvement was not achieved with steroid injections into the Tenon’s sac, and Nab-PTX and atezolizumab treatments were ceased. One month later, there was subjective improvement in her symptoms. Although many reports have indicated that cessation of chemotherapy has successfully improved CME, a specific treatment for CME has not yet been established. Clinicians should be aware of the ophthalmologic side effects and offer immediate treatment if symptoms develop.
Databáze: Directory of Open Access Journals
Nepřihlášeným uživatelům se plný text nezobrazuje