A Nationwide Analysis Evaluating the Safety of Using Acellular Dermal Matrix with Tissue Expander-Based Breast Reconstruction

Autor: Jessica Luo, Whitney D. Moss, Giovanna R. Pires, Irfan A. Rhemtulla, Megan Rosales, Gregory J. Stoddard, Jayant P. Agarwal, Alvin C. Kwok
Jazyk: angličtina
Rok vydání: 2022
Předmět:
Zdroj: Archives of Plastic Surgery, Vol 49, Iss 06, Pp 716-723 (2022)
Druh dokumentu: article
ISSN: 2234-6163
2234-6171
0042-1758
DOI: 10.1055/s-0042-1758638
Popis: Background In March 2021, the United States Food and Drug Administration (FDA) safety communication cautioned against the use of acellular dermal matrix (ADM) products in breast reconstruction and reiterated that the FDA does not approve ADM use in breast surgery. This study aims to assess the safety of ADM use in breast reconstruction. Methods Women who underwent ADM and non-ADM assisted tissue expander (TE)-based breast reconstruction were identified using the National Surgical Quality Improvement Program database (2012–2019). Trends of ADM use over time, and 30-day outcomes of surgical site infection (SSI), dehiscence, and unplanned reoperation were assessed. Results Of the 49,049 TE-based breast reconstructive cases, 42.4% were ADM assisted and 57.6% non-ADM assisted. From 2012 to 2019, the use of ADM increased from 26.1 to 55.6% (relative risk [RR] =1.10; p
Databáze: Directory of Open Access Journals
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