Development and implementation of evidence-based, nurse-leading early warning model and healthcare quality improvement project for transplant-associated thrombotic microangiopathy: a mixed-methods, before-and-after study

Autor: Xiaoyu Zhou, Yishan Ye, Aiyun Jin, Zhengwen Pan, Zhe Xu, Shuyi Ding, Jiali Yan, Yin Cheng, Yixuan Huang, Kai Cao, Wei Xie, Jianli Zhang, Liwei Xu, Weiwei Zhou, Lihua Huang
Jazyk: angličtina
Rok vydání: 2024
Předmět:
Zdroj: BMC Nursing, Vol 23, Iss 1, Pp 1-8 (2024)
Druh dokumentu: article
ISSN: 1472-6955
DOI: 10.1186/s12912-024-02093-7
Popis: Abstract Objective The early identification and diagnosis of transplant-associated thrombotic microangiopathy (TA-TMA) are essential yet difficult in patients underwent hematopoietic stem cell transplantation (HSCT). To develop an evidence-based, nurse-leading early warning model for TA-TMA, and implement the healthcare quality review and improvement project. Methods This study was a mixed-methods, before-and-after study. The early warning model was developed based on quality evidence from literature search. The healthcare quality review and improvement project mainly included baseline investigation of nurse, improvement action and effectiveness evaluation. The awareness and knowledge of early parameter of TA-TMA among nurses and the prognosis of patients underwent HSCT were compared before and after the improvement. Results A total of 1 guideline, 1 evidence synthesis, 4 expert consensuses, 10 literature reviews, 2 diagnostic studies, and 9 case series were included in the best evidence. The early warning model including warning period, high-risk characteristics and early manifestation of TA-TMA was developed. The improvement action, including staff training and assessment, suspected TA-TMA identification and patient education, was implemented. The awareness and knowledge rate of early parameter of TA-TMA among nurses significantly improved after improvement action (100% vs. 26.7%, P
Databáze: Directory of Open Access Journals
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