Tissue Doppler derived biphasic velocities during the pre and post-ejection phases: patterns, concordance and hemodynamic significance in health and disease

Autor: Alaa Mabrouk Salem Omar, Diana Maria Ronderos Botero, Javier Arreaza Caraballo, Ga Hee Kim, Yeraz Khachatoorian, Jaclyn Kliewer, Mohamed Ahmed Abdel Rahman, Osama Rifaie, Jonathan N. Bella, Edgar Argulian, Johanna Contreras
Jazyk: angličtina
Rok vydání: 2022
Předmět:
Zdroj: Cardiovascular Ultrasound, Vol 20, Iss 1, Pp 1-14 (2022)
Druh dokumentu: article
ISSN: 1476-7120
DOI: 10.1186/s12947-022-00287-0
Popis: Abstract Background Pre-(PRE) and post-ejection (POE) velocities by mitral annular tissue Doppler (TD) are biphasic and may be related to myocardial deformations. We investigated the predominance and concordance of TD-PRE and POE velocities and their effect on myocardial functions in controls and in heart failure (HF) patients. Methods Retrospectively, 84 HF patients [57.6 years, 28(33%) females, NYHA: 2.3 ± 0.6, EF: 55 ± 15%, 52(62%) preserved EF, and 32(38%) reduced EF], 42 normal young controls, and 26 asymptomatic age matched controls were included. Echocardiography was done and from mitral annular tissue Doppler recordings, the biphasic PRE and POE velocity signals were identified and compared between groups. Results While controls had almost always predominantly positive PRE and negative POE, HF had more negative PRE and positive POE. Moreover, almost all controls exhibited normal concordance (positive PRE and negative POE). HF exhibited more abnormal concordance which was significantly associated with worse NYHA, and parameters of diastolic and systolic functions. Opposite PRE and POE velocities correlated significantly in all groups (PREp vs POEn: young:r = 0.52, p
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