A minimal biochemical route towards de novo formation of synthetic phospholipid membranes

Autor: Ahanjit Bhattacharya, Roberto J. Brea, Henrike Niederholtmeyer, Neal K. Devaraj
Jazyk: angličtina
Rok vydání: 2019
Předmět:
Zdroj: Nature Communications, Vol 10, Iss 1, Pp 1-8 (2019)
Druh dokumentu: article
ISSN: 2041-1723
DOI: 10.1038/s41467-018-08174-x
Popis: The origin of phospholipids, the primary constituents of cell membranes, is uncertain. Here, the authors develop an in vitro system to synthesize phospholipid molecules from water-soluble single-chain amphiphilic precursors via a reaction catalysed by the mycobacterial ligase FadD10.
Databáze: Directory of Open Access Journals