Diverse Polyphenols from Hypericum faberi

Autor: Xin-Wen Zhang, Yan-Song Ye, Fan Xia, Xing-Wei Yang, Gang Xu
Jazyk: angličtina
Rok vydání: 2019
Předmět:
Zdroj: Natural Products and Bioprospecting, Vol 9, Iss 3, Pp 215-221 (2019)
Druh dokumentu: article
ISSN: 2192-2195
2192-2209
DOI: 10.1007/s13659-019-0206-1
Popis: Abstract Six new polyphenols with different isoprenylated xanthones, isoprenylated acylphloroglucinols, and chromone architectures, hyperfaberols A–F (1–6), were isolated from the whole plants of Hypericum faberi along with seven other related known compounds. In which hyperfaberols A/B (1/2) and 12–13 were isoprenylated xanthones, hyperfaberols C–E (3–5) and 8–11 were seven isoprenylated acylphloroglucinol derivatives, while 6–7 were two chromones. Their structures were elucidated by comprehensive analysis of their spectroscopic data as well as detailed comparison with the literature data. Compounds 1 and 11 showed cytotoxities against the human esophageal cancer cell line (ECA-109) and the pancreatic tumor cell line (PANC-1) in vitro, respectively. Graphical Abstract
Databáze: Directory of Open Access Journals
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