Metallosis: A New Form of Autoimmune/Autoinflammatory Syndrome Induced by Adjuvants Syndrome (ASIA)?

Autor: Rita Alexandra Vaz, Pedro Xavier, Sergio Brito, Jorge Dantas, Sofia Duque, Jose Guimarães Consciência, Luis Campos
Jazyk: angličtina
Rok vydání: 2019
Předmět:
Zdroj: European Journal of Case Reports in Internal Medicine (2019)
Druh dokumentu: article
ISSN: 2284-2594
DOI: 10.12890/2019_001034
Popis: Autoimmune/autoinflammatory syndrome induced by adjuvants (ASIA) is a new entity in which exposure to an adjuvant triggers an aberrant autoimmune response. Metallosis is a rare condition characterized by the deposition and build-up of metal debris in the soft tissues of the body associated with metal-on-metal (MOM) prosthetic devices. It can present with local/systemic symptoms and signs due to a chronic inflammatory host response. The authors present the case of a 51-year-old woman with a 6-month history of systemic complaints due to intoxication with metal ions from hip metallosis. This case highlights the importance of follow-up and continuous monitoring of patients with a hip prosthesis. As this is a rare condition, a patient presenting with unspecific symptoms such as ASIA syndrome induced by metallosis requires a high level of clinical suspicion as the removal of the adjuvant can resolve the condition.
Databáze: Directory of Open Access Journals