Dyslipidemia and peripheral arterial disease

Autor: Ajay Yadav, Vivek Sawant, Varinder Singh Bedi, Kanupriya Yadav
Jazyk: angličtina
Rok vydání: 2024
Předmět:
Zdroj: Indian Heart Journal, Vol 76, Iss , Pp S86-S89 (2024)
Druh dokumentu: article
ISSN: 0019-4832
90490088
DOI: 10.1016/j.ihj.2024.01.010
Popis: Peripheral arterial disease (PAD) affects 12 % of adult population and is increasing globally and in India. Peripheral arterial disease when associated with atherosclerosis in two or more other arterial beds such as coronary artery disease (CAD), mesenteric/renal artery and cerebrovascular disease (CVD), is known as polyvascular disease. The Reduction of Atherothrombosis for Continued Health (REACH) registry reported that 1 out of 6 patients had multi-vascular bed involvement. Progression of PAD to critical limb ischaemia (CLI) is seen in 1 % of affected patients per year, but patients who progress to CLI may have a 10- to 15-fold increased risk of cardiovascular death.The 2019 ECS/EAS guidelines for the management of dyslipidaemias have suggested that for primary or secondary prevention in very high risk, patients should follow a therapeutic regimen that achieves >50 % LDL-C reduction from baseline and an LDL-C goal of
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