THE RELEVANCE, BENEFITS AND CLINICAL PERSPECTIVES OF THE COMBINED TREATMENT OF OSTEOPOROSIS BASED ON BONE-ANABOLIC THERAPY

Autor: L A Marchenkova, E Yu Martynova
Jazyk: English<br />Russian
Rok vydání: 2015
Předmět:
Zdroj: Остеопороз и остеопатии, Vol 18, Iss 2, Pp 20-24 (2015)
Druh dokumentu: article
ISSN: 2072-2680
2311-0716
DOI: 10.14341/osteo2015220-24
Popis: Combination therapy of osteoporosis based on bone-anabolic and antiresorbtive agents has a great clinical perspective. An analysis of available publications shows that combination therapy is appropriate from the standpoint of increasing the effectiveness of treatment. Combination therapy can be executed as a simultaneous use of teriparatide with denosumab, raloxifene or hormonal therapy, and the subsequent administration of bisphosphonates, denosumab or raloxifene after treatment with teriparatide. The review presents the evidence-based data on the effect of combined and sequential regimens for osteoporosis fracture risk.
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