Gut microbiome is not associated with mild cognitive impairment in Parkinson’s disease

Autor: Velma T. E. Aho, Matthias Klee, Zied Landoulsi, Anna Heintz-Buschart, Lukas Pavelka, Anja K. Leist, Rejko Krüger, Patrick May, Paul Wilmes, on behalf of the NCER-PD Consortium
Jazyk: angličtina
Rok vydání: 2024
Předmět:
Zdroj: npj Parkinson's Disease, Vol 10, Iss 1, Pp 1-6 (2024)
Druh dokumentu: article
ISSN: 2373-8057
69227047
DOI: 10.1038/s41531-024-00687-1
Popis: Abstract Gut microbiome differences between people with Parkinson’s disease (PD) and control subjects without Parkinsonism are widely reported, but potential alterations related to PD with mild cognitive impairment (MCI) have yet to be comprehensively explored. We compared gut microbial features of PD with MCI (n = 58) to cognitively unimpaired PD (n = 60) and control subjects (n = 90) with normal cognition. Our results did not support a specific microbiome signature related to MCI in PD.
Databáze: Directory of Open Access Journals