Neutrophil levels upon admission for the assessment of acute pulmonary embolism with intermediate- and high-risk: an indicator of thrombosis and inflammation

Autor:	Rui Peng, Weihua Yin, Fang Wang, Xiangfeng Cong, Bin Lu, Lu Hua, Xi Chen
Jazyk:	angličtina
Rok vydání:	2023
Předmět:	Neutrophils Acute pulmonary embolism risk classification Inflammation Thrombosis Diseases of the blood and blood-forming organs RC633-647.5
Zdroj:	Thrombosis Journal, Vol 21, Iss 1, Pp 1-11 (2023)
Druh dokumentu:	article
ISSN:	1477-9560
DOI:	10.1186/s12959-023-00471-w
Popis:	Abstract Background Risk prediction rules are important to establish appropriate treatment and management strategy for patients with different risk classification of pulmonary embolism (PE). Neutrophils are considered to be related to PE as an essential marker of inflammation. However, few studies have reported the association between neutrophil levels and risk classification of acute PE (APE). The aim of this study was to investigate the role of neutrophil levels upon admission in the assessment of risk classification of APE. Methods A total of 299 consecutive APE patients and 90 patients without APE confirmed by computed tomographic pulmonary angiography were retrospectively screened. APE patients were stratified into two subgroups according to clinical guidelines: low- (n = 233) and intermediate- and high-risk (n = 60) APE. Results The neutrophil levels in intermediate- and high-risk APE patients were significantly higher compared to low-risk APE or non-APE patients (P
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