Decision Tool for Herpes B Virus Antiviral Prophylaxis after Macaque-Related Injuries in Research Laboratory Workers

Autor: Sapha Barkati, Hashim Ba Taher, Elizabeth Beauchamp, Cédric P. Yansouni, Brian J. Ward, Michael D. Libman
Jazyk: angličtina
Rok vydání: 2019
Předmět:
Zdroj: Emerging Infectious Diseases, Vol 25, Iss 9, Pp 1-6 (2019)
Druh dokumentu: article
ISSN: 1080-6040
1080-6059
DOI: 10.3201/eid2509.190045
Popis: Macaque-related injuries among primate workers can lead to a potentially fatal B virus encephalomyelitis. We describe a decision tool for evaluating the need for antiviral postexposure prophylaxis and provide a retrospective review of the injuries assessed in our center after its implementation in 2010. Among the injuries studied (n = 251), 40.6% were categorized as high-risk (prophylaxis recommended), 44.2% moderate-risk (consider prophylaxis), and 15.1% low-risk (prophylaxis not recommended). Ten percent of low-risk and 98% of high-risk injuries received prophylaxis (p
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