A snapshot of antimicrobial resistance in Mexico. Results from 47 centers from 20 states during a six-month period.

Autor: Elvira Garza-González, Rayo Morfín-Otero, Soraya Mendoza-Olazarán, Paola Bocanegra-Ibarias, Samantha Flores-Treviño, Eduardo Rodríguez-Noriega, Alfredo Ponce-de-León, Domingo Sanchez-Francia, Rafael Franco-Cendejas, Sara Arroyo-Escalante, Consuelo Velázquez-Acosta, Fabián Rojas-Larios, Luis J Quintanilla, Joyarit Y Maldonado-Anicacio, Rafael Martínez-Miranda, Heidy L Ostos-Cantú, Abraham Gomez-Choel, Juan L Jaime-Sanchez, Laura K Avilés-Benítez, José M Feliciano-Guzmán, Cynthia D Peña-López, Carlos A Couoh-May, Aaron Molina-Jaimes, Elda G Vázquez-Narvaez, Joaquín Rincón-Zuno, Raúl Rivera-Garay, Aurelio Galindo-Espinoza, Andrés Martínez-Ramirez, Javier P Mora, Reyna E Corte-Rojas, Ismelda López-Ovilla, Víctor A Monroy-Colin, Juan M Barajas-Magallón, Cecilia T Morales-De-la-Peña, Efrén Aguirre-Burciaga, Mabel Coronado-Ramírez, Alina A Rosales-García, María-de-J Ayala-Tarín, Silvia Sida-Rodríguez, Bertha A Pérez-Vega, América Navarro-Rodríguez, Gloria E Juárez-Velázquez, Carlos Miguel Cetina-Umaña, Juan P Mena-Ramírez, Jorge Canizales-Oviedo, Martha Irene Moreno-Méndez, Daniel Romero-Romero, Alejandra Arévalo-Mejía, Dulce Isabel Cobos-Canul, Gilberto Aguilar-Orozco, Jesús Silva-Sánchez, Adrián Camacho-Ortiz
Jazyk: angličtina
Rok vydání: 2019
Předmět:
Zdroj: PLoS ONE, Vol 14, Iss 3, p e0209865 (2019)
Druh dokumentu: article
ISSN: 1932-6203
DOI: 10.1371/journal.pone.0209865
Popis: AIM:We aimed to assess the resistance rates of antimicrobial-resistant, in bacterial pathogens of epidemiological importance in 47 Mexican centers. MATERIAL AND METHODS:In this retrospective study, we included a stratified sample of 47 centers, covering 20 Mexican states. Selected isolates considered as potential causatives of disease collected over a 6-month period were included. Laboratories employed their usual methods to perform microbiological studies. The results were deposited into a database and analyzed with the WHONET 5.6 software. RESULTS:In this 6-month study, a total of 22,943 strains were included. Regarding Gram-negatives, carbapenem resistance was detected in ≤ 3% in Escherichia coli, 12.5% in Klebsiella sp. and Enterobacter sp., and up to 40% in Pseudomonas aeruginosa; in the latter, the resistance rate for piperacillin-tazobactam (TZP) was as high as 19.1%. In Acinetobacter sp., resistance rates for cefepime, ciprofloxacin, meropenem, and TZP were higher than 50%. Regarding Gram-positives, methicillin resistance in Staphylococcus aureus (MRSA) was as high as 21.4%, and vancomycin (VAN) resistance reached up to 21% in Enterococcus faecium. Acinetobacter sp. presented the highest multidrug resistance (53%) followed by Klebsiella sp. (22.6%) and E. coli (19.4%). CONCLUSION:The multidrug resistance of Acinetobacter sp., Klebsiella sp. and E. coli and the carbapenem resistance in specific groups of enterobacteria deserve special attention in Mexico. Vancomycin-resistant enterococci (VRE) and MRSA are common in our hospitals. Our results present valuable information for the implementation of measures to control drug resistance.
Databáze: Directory of Open Access Journals
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