Complete, refractory dysphagia in a dermatomyositis patient with positive anti-NXP-2 antibodies

Autor:	Claudia Cobilinschi, Cristian Cobilinschi, Alexandra Constantinescu, Ruxandra Ionescu, Daniela Opris-Belinski
Jazyk:	angličtina
Rok vydání:	2021
Předmět:	systemic lupus erythematosus late-onset elderly onset serositis arthritis Medicine Immunologic diseases. Allergy RC581-607
Zdroj:	Romanian Journal of Rheumatology, Vol 30, Iss 4, Pp 169-173 (2021)
Druh dokumentu:	article
ISSN:	1843-0791 2069-6086
DOI:	10.37897/RJR.2021.4.7
Popis:	Dermatomyositis (DM) is a rare autoimmune disorder defined by weakness of the striated muscles and a distinctive skin rash. Dysphagia is a serious symptom that can be difficult to manage, severely impacting quality of life and long-term survival. The aim of this report is to highlight a case of an anti-NXP-2 positive DM with severe dysphagia refractory to multiple therapies, including steroids, cyclophosphamide and intravenous immunoglobulins. Anti-NXP-2 autoantibodies indicate a specific disease phenotype adding severe muscle weakness, dysphagia, peripheral edema and underlying malignancy.
Databáze:	Directory of Open Access Journals
Externí odkaz:	https://doaj.org/article/89573d409050407b821619d6f1dbb486 Zobrazit plný text záznamu View record in DOAJ Plný text ve formátu PDF