Advances in IgA nephropathy management, from pathological insights to personalized treatment

Autor:	Mitra Shavakhi, Agha Wajdan Baqir
Jazyk:	angličtina
Rok vydání:	2023
Předmět:	iga nephropathy targeted-release budesonide corticosteroid oxford classification mest-c score Pathology RB1-214 Internal medicine RC31-1245 Other systems of medicine RZ201-999
Zdroj:	Journal of Nephropathology, Vol 12, Iss 4, Pp e21480-e21480 (2023)
Druh dokumentu:	article
ISSN:	2251-8363 2251-8819
DOI:	10.34172/jnp.2023.21480
Popis:	IgA nephropathy is a common glomerulonephritis with variable clinical outcomes. The optimal treatment for this condition remains uncertain, and corticosteroid therapy is reserved for patients unresponsive to supportive treatment. The histopathologic examination has a significant role in the diagnosis and prognosis of IgA nephropathy, but its role in the initiation of corticosteroid therapy is still under debate. Recently, targeted release formulation (TRF)-budesonide has emerged as a promising treatment due to its localized delivery to the gut and low systemic adverse effects. This brief review aims to assess recent advancements in IgA nephropathy management, focusing on applying Oxford classification in guiding corticosteroid therapy.
Databáze:	Directory of Open Access Journals
Externí odkaz:	https://doaj.org/article/894c3fa6c831439f980af4bfaf9a849f Zobrazit plný text záznamu View record in DOAJ Plný text ve formátu PDF