Relationship between the High Fatty Liver Index and Risk of Fracture

Autor: Min-Ji Kim, Min-Su Kim, Han-Byul Lee, Jae-Hyung Roh, Jae-Han Jeon
Jazyk: angličtina
Rok vydání: 2023
Předmět:
Zdroj: Gut and Liver, Vol 17, Iss 1, Pp 119-129 (2023)
Druh dokumentu: article
ISSN: 1976-2283
DOI: 10.5009/gnl210571
Popis: Background/Aims: The prevalence of nonalcoholic fatty liver disease (NAFLD) has increased rapidly as a consequence of more sedentary lifestyles and a Westernized diet. Fracture is a major clinical problem in older people, but few large-scale cohort studies have evaluated the relationship between NAFLD and fracture. Therefore, we aimed to determine whether the fatty liver index (FLI), which represents the severity of NAFLD, can predict fracture risk. Methods: We analyzed the relationship between the FLI and incident fracture using multivariate Cox proportional hazards models and data for 180,519 individuals who underwent National Health check-ups in the Republic of Korea between 2009 and 2014. Results: A total of 2,720 participants (1.5%) were newly diagnosed with fracture during the study period (median 4.6 years). The participants were grouped according to FLI quartiles (Q1, 0 to
Databáze: Directory of Open Access Journals