| Autor: |
Sofie Lundgren, Thomas Saeys, Fredrik Karlsson, Katarina Olofsson, Patric Blomstedt, Jan Linder, Erik Nordh, Hamayun Zafar, Jan van Doorn |
| Jazyk: |
angličtina |
| Rok vydání: |
2011 |
| Předmět: |
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| Zdroj: |
Parkinson's Disease, Vol 2011 (2011) |
| Druh dokumentu: |
article |
| ISSN: |
2042-0080 |
| DOI: |
10.4061/2011/658956 |
| Popis: |
Deep brain stimulation of the subthalamic nucleus (STN-DBS) in patients with Parkinson's disease (PD) affects speech inconsistently. Recently, stimulation of the caudal zona incerta (cZi-DBS) has shown superior motor outcomes for PD patients, but effects on speech have not been systematically investigated. The aim of this study was to compare the effects of cZi-DBS and STN-DBS on voice intensity in PD patients. Mean intensity during reading and intensity decay during rapid syllable repetition were measured for STN-DBS and cZi-DBS patients (eight patients per group), before- and 12 months after-surgery on- and off-stimulation. For mean intensity, there were small significant differences on- versus off-stimulation in each group: 74.2 (2.0) dB contra 72.1 (2.2) dB (𝑃=.002) for STN-DBS, and 71.6 (4.1) dB contra 72.8 (3.4) dB (𝑃=.03) for cZi-DBS, with significant interaction (𝑃 |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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