The effect of ciplukan (Physalis angulate Linn.) leaf extract on the testicles of rats (Rattus norvegicus) exposed to heat
| Autor: | Annisa Nur Fitria Rahma, Sherina Lashita Candrakirana, Rimayanti Rimayanti, Tri Wahyu Suprayogi, Budi Utomo, Tatik Hernawati, Anwar Ma'ruf, Nove Hidajati, Kadek Rachmawati, Eka Pramyrtha Hestianah, Hani Plumeriastuti |
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| Jazyk: | angličtina |
| Rok vydání: | 2024 |
| Předmět: | |
| Zdroj: | Ovozoa: Journal of Animal Reproduction, Vol 13, Iss 1, Pp 30-38 (2024) |
| Druh dokumentu: | article |
| ISSN: | 2302-6464 2722-967X |
| DOI: | 10.20473/ovz.v13i1.2024.30-38 |
| Popis: | This study aims to determine the effect of administration of ciplukan (Physalis angulate Linn.) leaf extract on the variables of testicular weight, seminiferous tubules diameter, and spermatozoa plasma membrane integrity of rats (Rattus norvegicus) exposed to heat as model animals. Rats were divided randomly into five groups. In the NC group, rats were not exposed to heat and were only given 1% Na-CMC. In the PC, T1, T2, and T3 rats were exposed to heat followed by administration of 1% Na-CMC, 100, 200, and 400 mg/kg bw of ciplukan leaf extract (CLE) in 1% Na-CMC. Heat exposure at 40°C was conducted for 60 minutes every day for 21 days. On day-22, all rats were sacrificed for testicular evaluation. The results showed that all variables in the PC group were lower (p 0.05) from the NC group. However, the diameter of the seminiferous tubules in the T3 group were lower (p |
| Databáze: | Directory of Open Access Journals |
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