Prognostic and risk factors in patients with metastatic bone disease of an upper extremity

Autor: Taweechok Wisanuyotin, Winai Sirichativapee, Chat Sumnanoont, Permsak Paholpak, Pat Laupattarakasem, Kamonsak Sukhonthamarn, Weerachai Kosuwon
Jazyk: angličtina
Rok vydání: 2018
Předmět:
Zdroj: Journal of Bone Oncology, Vol 13, Iss , Pp 71-75 (2018)
Druh dokumentu: article
ISSN: 2212-1374
DOI: 10.1016/j.jbo.2018.09.007
Popis: Background: The aim of this study was to evaluate survival of metastatic bone disease of an upper extremity, and to identify the prognostic factors that influence survival. Methods: Patients with metastatic bone disease of an upper extremity between 2008 and 2015 were reviewed from the database of a tertiary university hospital. Results: Of 102 patients, 48 males and 54 females with a median age of 61 (range, 28–82 years), the humerus (64.7%), clavicle (13.7%), and scapula (12.7%) were the common sites for bone metastasis of an upper extremity. Fifty-nine (57.8%) presented with pathologic fracture. No history of cancer was found in 76.5% of patients. The mean onset of metastatic bone disease after the first diagnosis of primary cancer was 4.74 ± 14.07 months (range, 0–84 months). Lung (31.4%) was the most common primary cancer followed by liver (14.7%), breast (12.7%), thyroid (7.8%), and renal (3.9%). Eighty-two cases (80.39%) died from the disease such that the median survival was 4.08 months (95% CI 2.57–6.17). The significant risk factors were the type of primary tumor (P
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