Cytotoxic effect of chamomile (Matricaria recutita) and marigold (Calendula officinalis) extracts on human melanoma SK-MEL-2 and epidermoid carcinoma KB cells

Autor:	Katrin Sak, Thi Hoai Nguyen, Viet Duc Ho, Thi Thao Do, Ain Raal
Jazyk:	angličtina
Rok vydání:	2017
Předmět:	matricaria recutita calendula officinalis anticancer effect human melanoma non-melanoma skin cancer Medicine
Zdroj:	Cogent Medicine, Vol 4, Iss 1 (2017)
Druh dokumentu:	article
ISSN:	2331-205X 2331205X
DOI:	10.1080/2331205X.2017.1333218
Popis:	The aim of the present study was to evaluate the potential anticancer action of extracts prepared from german chamomile (Matricaria recutita L.)and pot marigold (Calendula officinalis L.) to human melanoma and epidermoid carcinoma cells. Sulforhodamine B assay was used to measure the cytotoxic activity of methanolic extracts from flowers of chamomile and marigold. The cytotoxic activity of extract of chamomile flowers on melanoma cells (IC50 value 40.7 μg/ml) was approximately twofold higher than on epidermoid carcinoma cells (IC50 value 71.4 μg/ml). In the present study, the anticancer action of extracts prepared from german chamomile flowers on human melanoma and non-melanoma skin cancer cells (SK-MEL-2 melanoma and KB epidermoid carcinoma cells) is described for the first time.
Databáze:	Directory of Open Access Journals
Externí odkaz:	https://doaj.org/article/89129711a1b6460085a68bcab05081cf Zobrazit plný text záznamu View record in DOAJ Plný text ve formátu PDF Plný text ve formátu HTML
Nepřihlášeným uživatelům se plný text nezobrazuje	K zobrazení výsledku je třeba se přihlásit.