Diagnosis of multifocal atherosclerosis using the Celermajer test

Autor: M. V. Zhatkina, N. E. Gavrilova, Yu. K. Makarova, V. A. Metelskaya, B. A. Rudenko, O. M. Drapkina
Jazyk: ruština
Rok vydání: 2020
Předmět:
Zdroj: Кардиоваскулярная терапия и профилактика, Vol 19, Iss 5 (2020)
Druh dokumentu: article
ISSN: 1728-8800
2619-0125
DOI: 10.15829/1728-8800-2020-2638
Popis: Aim. To study the effectiveness of determining atherosclerosis and its severity in the brachiocephalic (BCA), coronary (CA) and femoral (FA) arteries based on the endothelial function test proposed by Celermajer DS.Material and methods. The study included 216 patients: 115 men and 101 women aged 24-87 years (mean age, 61,5±10,73 years). All patients underwent coronary angiography to assess the presence and severity of coronary artery atherosclerosis, and duplex ultrasound of BCA and FA atherosclerosis. The functional activity of the endothelium was assessed using the Celermajer test.Results. Depending on the presence and severity of atherosclerosis in each arterial region (BCA, CA and FA), patients were divided into the following groups: group 1 — patients with intact arteries, group 2 — patients with moderate atherosclerosis, group 3 — patients with severe atherosclerosis. Comparative analysis of brachial artery diameters identified by the Celermajer test revealed a significant difference between the groups. Comparison of Celermajer test results in CA groups was as follows: groups 1 and 2 (p=0,34), groups 1 and 3 (p
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