Data on the effect of knockout of cytohesin-1 in myelination-related protein kinase signaling

Autor: Ruri Tsuneishi, Naoto Matsumoto, Misa Itaoka, Yuri Urai, Minami Kaneko, Natsumi Watanabe, Shou Takashima, Yoichi Seki, Takako Morimoto, Hiroyuki Sakagami, Yuki Miyamoto, Junji Yamauchi
Jazyk: angličtina
Rok vydání: 2017
Předmět:
Zdroj: Data in Brief, Vol 15, Iss , Pp 234-239 (2017)
Druh dokumentu: article
ISSN: 2352-3409
DOI: 10.1016/j.dib.2017.09.024
Popis: Cytohesin-1 is the guanine-nucleotide exchange factor of Arf6, a small GTPase of Arf family, and participates in cellular morphological changes. Knockout mice of cytohesin-1 exhibit decreased myelination of neuronal axons in the peripheral nervous system (PNS) âPhosphorylation of cytohesin-1 by Fyn is required for initiation of myelination and the extent of myelination during development (Yamauchi et al., 2012) [1]â. Herein we provide the data regarding decreased phosphorylation levels of protein kinases involved in two major myelination-related kinase cascades in cytohesin-1 knockout mice. Keywords: Cytohesin-1, Myelination, Peripheral nervous system, Protein kinase, Signaling
Databáze: Directory of Open Access Journals