Focused ultrasound thalamotomy for tremor treatment impacts the cerebello-thalamo-cortical network

Autor: Louisa Dahmani, Yan Bai, Meiling Li, Jianxun Ren, Lunhao Shen, Jianjun Ma, Haiyang Li, Wei Wei, Pengyu Li, Danhong Wang, Lei Du, Weigang Cui, Hesheng Liu, Meiyun Wang
Jazyk: angličtina
Rok vydání: 2023
Předmět:
Zdroj: npj Parkinson's Disease, Vol 9, Iss 1, Pp 1-14 (2023)
Druh dokumentu: article
ISSN: 2373-8057
DOI: 10.1038/s41531-023-00543-8
Popis: Abstract High-intensity Magnetic Resonance-guided Focused Ultrasound (MRgFUS) is a recent, non-invasive line of treatment for medication-resistant tremor. We used MRgFUS to produce small lesions in the thalamic ventral intermediate nucleus (VIM), an important node in the cerebello-thalamo-cortical tremor network, in 13 patients with tremor-dominant Parkinson’s disease or essential tremor. Significant tremor alleviation in the target hand ensued (t(12) = 7.21, p
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