Overexpression of annexin 1 in the development and differentiation of urothelial carcinoma

Autor: Wan-Yi Kang, Wan-Tzu Chen, Ya-Chun Huang, Yue-Chiu Su, Chee-Yin Chai
Jazyk: angličtina
Rok vydání: 2012
Předmět:
Zdroj: Kaohsiung Journal of Medical Sciences, Vol 28, Iss 3, Pp 145-150 (2012)
Druh dokumentu: article
ISSN: 1607-551X
DOI: 10.1016/j.kjms.2011.10.004
Popis: This study investigates the expression of annexin 1 in urothelial carcinoma (UC) and its relation with clinicopathologic factors, and evaluates its potential clinical significance. Annexin 1 expression was analyzed by immunohistochemical staining with manual tissue microarrays and Western blot in UC. Immunohistochemical analysis of UC in tissue microarrays showed that annexin 1 protein was 76.5% (150/196) positive, which was markedly increased compared with that in the normal urothelium 20.8% (5/24) (p
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