| Autor: |
Reiya Yabuki, Koki Nishimura, Yuta Sawada, Masaaki Fuki, Yasuhiro Kobori, Nobuhiro Yanai |
| Jazyk: |
angličtina |
| Rok vydání: |
2025 |
| Předmět: |
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| Zdroj: |
Journal of Magnetic Resonance Open, Vol 22, Iss , Pp 100181- (2025) |
| Druh dokumentu: |
article |
| ISSN: |
2666-4410 |
| DOI: |
10.1016/j.jmro.2024.100181 |
| Popis: |
Chemically induced dynamic electron polarization (CIDEP) generates radical electron spins with high polarization at room temperature by quenching the photo-excited state of chromophores, which is useful for microwave-free optical dynamic nuclear polarization (DNP) in solution. While nitroxyl (TEMPO) radicals are typically used for this purpose, we show that a tris(2,4,6-trichlorophenyl)-methyl (TTM) radical derivative shows greater electron spin polarization than TEMPO by CIDEP using porphyrin chromophores. This is attributed to the longer spin-lattice relaxation time of TTM radicals, with a contribution of efficient quenching of chromophore photo-excited state by energy transfer from the triplet state of porphyrins to the doublet state of the TTM radicals. The porphyrin-TTM pair shows a larger nuclear spin polarization under continuous laser excitation than the porphyrin-TEMPO pair because of the larger polarization and longer spin-lattice relaxation time of the TTM radical electron spins. This work demonstrates the first example of in-solution CIDEP and optically-driven DNP using TTM radicals, opening new opportunities in a wide range of biological and medical applications. |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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