Red blood cell derived nanocarrier drug delivery system: A promising strategy for tumor therapy

Autor: Xin Wang, Kuirong Mao, Xiaonan Zhang, Yuning Zhang, Yong‐Guang Yang, Tianmeng Sun
Jazyk: angličtina
Rok vydání: 2024
Předmět:
Zdroj: Interdisciplinary Medicine, Vol 2, Iss 3, Pp n/a-n/a (2024)
Druh dokumentu: article
ISSN: 2832-6245
DOI: 10.1002/INMD.20240014
Popis: Abstract Nano drug delivery systems have been widely used in tumor therapy. Researchers have been devoted to exploring novel nano‐carriers to prolong circulation time biocompatibility and tumor targeting efficiency in vivo. Erythrocyte membranes as bionic nano‐drug delivery systems have attracted more attention recently. There are abundant red blood cells (RBCs) in circulation, which are natural carriers for nanomaterial delivery. There are mainly two strategies to use RBCs as nanomaterial carriers: RBC‐hitchhiking and bionic nanomaterial coated with erythrocyte membrane loading with drugs. Although nano‐carrier based on RBCs have yielded some progress, the mechanism of mutual effect between nanoparticles and RBCs is still unclear. Here, we review the effects of nanoparticles on RBCs (morphology and function, etc) and application of RBCs membrane as nano‐drug delivery carriers in tumor therapy.
Databáze: Directory of Open Access Journals