Experimental Infection of Squirrel Monkeys with Nipah Virus

Autor: Philippe Marianneau, Vanessa Guillaume, K. Thong Wong, Munisamy Badmanathan, Ren Yih Looi, Séverine Murri, Philippe Loth, Noël Tordo, T. Fabian Wild, Branka Horvat, Hugues Contamin
Jazyk: angličtina
Rok vydání: 2010
Předmět:
Zdroj: Emerging Infectious Diseases, Vol 16, Iss 3, Pp 507-510 (2010)
Druh dokumentu: article
ISSN: 1080-6040
1080-6059
DOI: 10.3201/eid1603.091346
Popis: We infected squirrel monkeys (Saimiri sciureus) with Nipah virus to determine the monkeys’ suitability for use as primate models in preclinical testing of preventive and therapeutic treatments. Infection of squirrel monkeys through intravenous injection was followed by high death rates associated with acute neurologic and respiratory illness and viral RNA and antigen production.
Databáze: Directory of Open Access Journals