Experimental Infection of Squirrel Monkeys with Nipah Virus
Autor: | Philippe Marianneau, Vanessa Guillaume, K. Thong Wong, Munisamy Badmanathan, Ren Yih Looi, Séverine Murri, Philippe Loth, Noël Tordo, T. Fabian Wild, Branka Horvat, Hugues Contamin |
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Jazyk: | angličtina |
Rok vydání: | 2010 |
Předmět: | |
Zdroj: | Emerging Infectious Diseases, Vol 16, Iss 3, Pp 507-510 (2010) |
Druh dokumentu: | article |
ISSN: | 1080-6040 1080-6059 |
DOI: | 10.3201/eid1603.091346 |
Popis: | We infected squirrel monkeys (Saimiri sciureus) with Nipah virus to determine the monkeys’ suitability for use as primate models in preclinical testing of preventive and therapeutic treatments. Infection of squirrel monkeys through intravenous injection was followed by high death rates associated with acute neurologic and respiratory illness and viral RNA and antigen production. |
Databáze: | Directory of Open Access Journals |
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