Flavonoids from Limau Peel (Citrus amblycarpa (Hassk.) Ochse) and Their Antioxidant Activity

Autor: Kristin Shinta Dewi, Euis Julaeha, Kindi Farabi, Unang Supratman
Jazyk: English<br />Indonesian
Rok vydání: 2022
Předmět:
Zdroj: Molekul, Vol 17, Iss 2, Pp 193-199 (2022)
Druh dokumentu: article
ISSN: 1907-9761
2503-0310
DOI: 10.20884/1.jm.2022.17.2.5430
Popis: Citrus amblycarpa (Hassk.) Ochse is an endemic Indonesian plant from West Java. This study aims to determine the chemical structure of the flavonoid compounds of C. amblycarpa peel ethanol extract and their antioxidant activity. Three flavonoid compounds, namely 5-hydroxy-3',4',6,7,8-pentamethoxyflavone (1), 8-hydroxy-3,3',4',5,6,7-hexamethoxyflavone (2), and 3',4',5,6,7,8-hexamethoxyflavone (3), were isolated for the first time from the ethanol extract of C. amblycarpa peel. Their chemical structure was determined by spectroscopic methods (MS, IR, 1H-NMR, 13C-NMR, and DEPT) and compared with previous reported spectral data. Furthermore, these compounds were evaluated for their antioxidant activity using the DPPH method. The results showed that 8-hydroxy-3,3',4',5,6,7-hexamethoxyflavone (2) has the highest antioxidant activity with IC50 value of 121.09 ± 0.24 ppm.
Databáze: Directory of Open Access Journals