What would be the impact of COVID-19 on liver function of a patient with chronic hepatitis B? About a case and literature review
| Autor: | Khoury M'bodj, Hakima Abid, Najdi Adil, Mohammed El Abkari, Nourdin Aqodad |
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| Jazyk: | English<br />French |
| Rok vydání: | 2021 |
| Předmět: | |
| Zdroj: | The Pan African Medical Journal, Vol 38, Iss 225 (2021) |
| Druh dokumentu: | article |
| ISSN: | 1937-8688 04834526 |
| DOI: | 10.11604/pamj.2021.38.225.28123 |
| Popis: | Liver damage during COVID-19 disease has been described in numerous studies. Its mechanism is poorly understood. It is mainly reserved for severe forms and is manifested by abnormalities of the hepatic assessment and more particularly cytolysis. Particular attention must be paid to patients with chronic liver disease, both in terms of follow-up and treatment. We wanted to know the evolution of COVID-19 and its treatment, on the liver function of a 27-year-old patient followed for chronic non-cirrhotic hepatitis B at the Hassan II University Hospital in Fez. Our patient had stopped the antiviral B treatment and presented COVID-19 infection with minimal to moderate impairment. The initial evaluation showed cytolysis at 4 times upper limit of normal (ULN). Management consisted in the immediate resumption of Tenofovir in combination with hydroxychloroquine (HCQ) and azythromycin with good clinical and biological evolution. |
| Databáze: | Directory of Open Access Journals |
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