Derivation of induced pluripotent stem cell SJTUi003-A from a 69-year-old Chinese Han Sporadic Alzheimer’s disease patient with APOEε3/ε4 genetic background

Autor: Hui Li, Bei Zhang, Zhiqiang Shi, Hui Wu, Shuya Mei, Tianyi Ai, An Shi, Lihui Wang, Mingli Zhu, Jiajia Tang
Jazyk: angličtina
Rok vydání: 2023
Předmět:
Zdroj: Stem Cell Research, Vol 71, Iss , Pp 103142- (2023)
Druh dokumentu: article
ISSN: 1873-5061
DOI: 10.1016/j.scr.2023.103142
Popis: Alzheimer’s disease (AD) is an age-related and progressive neurodegenerative disease. In this study, we generated an induced pluripotent stem cell (iPSC) line from the dermal fibroblasts of a 69-year-old female patient carrying APOEε3/ε4 allele and diagnosed with sporadic AD. The iPSC line will be a useful tool for investigating the pathogenesis mechanisms and for drug tests in AD.
Databáze: Directory of Open Access Journals