Possible role of alpha-lipoic acid in the treatment of peripheral nerve injuries

Autor: Ranieri Maurizio, Sciuscio Manuela, Cortese Annamaria, Stasi Marilena, Panza Francesco, Megna Marisa, Fiore Pietro, Santamato Andrea
Jazyk: angličtina
Rok vydání: 2010
Předmět:
Zdroj: Journal of Brachial Plexus and Peripheral Nerve Injury, Vol 5, Iss 1, p 15 (2010)
Druh dokumentu: article
ISSN: 1749-7221
DOI: 10.1186/1749-7221-5-15
Popis: Abstract Recent findings on the antioxidant effects of pretreatment with α-lipoic acid (α-LA) on the crush injury of rat sciatic nerve confirm the possible usefulness of α-LA administration in humans with peripheral nerve injuries. We discussed this issue in relation with our recent results in which the combined employment of α-LA and γ-linolenic acid with a rehabilitation program for six weeks reduced sensory symptoms and neuropathic pain in patients with compressive radiculopathy syndrome from disc-nerve root conflict in comparison with patients submitted to rehabilitation program alone for six weeks.
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