| Autor: |
Sabato D’Auria, Annalisa Vitale, Luigi Zeni, Tullio Labella, Pierangelo Orlando, Giuseppe Ruggiero, Maria Staiano, Micaela Tartaglia, Luisa Iozzino, Paola Ringhieri, Nunzio Cennamo, Vincenzo Aurilia, Viviana Scognamiglio |
| Jazyk: |
angličtina |
| Rok vydání: |
2007 |
| Předmět: |
|
| Zdroj: |
Sensors, Vol 7, Iss 10, Pp 2484-2491 (2007) |
| Druh dokumentu: |
article |
| ISSN: |
1424-8220 |
| DOI: |
10.3390/s7102484 |
| Popis: |
D-Galactose/D-glucose-binding protein from E. coli (GGBP) is a monomer thatbinds glucose with high affinity. The protein structure of GGBP is organized in twoprincipal domains linked by a hinge region that form the sugar-binding site. In this workwe show that the mutant form of GGBP at the amino acid position 182 can be utilized as aprobe for the development of a non-consuming analyte fluorescence biosensor to monitorthe glucose level in diabetes health care. |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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