Neurosarcoidosis Associated with Psychiatric Symptoms: Case Report

Autor: Maick Wilen Fernandes Neves, Paulo Henrique Pires de Aguiar, Telmo Augusto Barba Belsuzarri, Wolnei Marques Zeviani, João Flavio de Araújo Mattos, Juliano Nery Navarro, Renata de Melo Braga Marques, Letícia Marissol de Souza Francisco
Jazyk: angličtina
Rok vydání: 2017
Předmět:
Zdroj: Brazilian Neurosurgery, Vol 36, Iss 03, Pp 185-189 (2017)
Druh dokumentu: article
ISSN: 0103-5355
2359-5922
DOI: 10.1055/s-0037-1606290
Popis: Abstract Background Sarcoidosis is a granulomatous disease predominant in women and black men that has inflammatory origin of unknown etiology; neurosarcoidosis is a rare and critical presentation of the disease. Case description A 26-year-old black female presented frontal headache for 1 year, as well as behavioral and mood changes for 15 days. Skull tomography and nuclear magnetic imaging of the skull revealed damaged meninges, a right frontal bone lesion, and an intraparenchymal contrast-enhancing lesion. Screening with computed tomography (CT) scans was performed, and it showed signs of bronchiectasis in the lower third of the right lung, but it was asymptomatic. The biopsy showed signs of reactional lesion with the presence of non-caseating granulomas. After the treatment with corticosteroids, the patient presented progressive improvement. Conclusions Neurosarcoidosis is a rare and critical pathology of sarcoidosis that presents a lytic bone lesion and clinical psychiatric symptoms; neurosarcoidosis is also rare in the literature.
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