Efficacy of 7-Day and 14-Day Triple Therapy Regimens for the Eradication of Helicobacter pylori: A Comparative Study in a Cohort of Romanian Patients
| Autor: | Stefan Sorin Arama, Catalin Tiliscan, Cristina Negoita, Alexandru Croitoru, Victoria Arama, Carmen Marina Mihai, Florinel Pop, Amit Garg |
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| Jazyk: | angličtina |
| Rok vydání: | 2016 |
| Předmět: | |
| Zdroj: | Gastroenterology Research and Practice, Vol 2016 (2016) |
| Druh dokumentu: | article |
| ISSN: | 1687-6121 1687-630X |
| DOI: | 10.1155/2016/5061640 |
| Popis: | Objective. This study compared the eradication rates of of Helicobacter pylori (HP) infection by a 7-day and 14-day anti-HP regimen. Materials and Methods. An open, randomized, prospective study was performed to evaluate the response to anti-HP treatment in adult HP-positive patients following a 7-day course (Regimen A) of a proton pump inhibitor in association with clarithromycin and amoxicillin compared to a 14-day course (Regimen B). Gastric biopsies were performed at baseline and two months after anti-HP treatment. Results. Seventy-eight patients aged 18–64 years (28 males, 50 females) diagnosed with HP infection were included. Fifty-two (66.7%) patients received Regimen B and 26 (33.3%) Regimen A. The overall eradication rate was 70.5%. Better treatment response (p |
| Databáze: | Directory of Open Access Journals |
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