Autor: |
Andrea Dalecka, Anna Bartoskova Polcrova, Hynek Pikhart, Martin Bobak, Albert J. Ksinan |
Jazyk: |
angličtina |
Rok vydání: |
2024 |
Předmět: |
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Zdroj: |
BMC Public Health, Vol 24, Iss 1, Pp 1-9 (2024) |
Druh dokumentu: |
article |
ISSN: |
1471-2458 |
DOI: |
10.1186/s12889-024-17960-w |
Popis: |
Abstract Background Biological aging reflects a decline in the functions and integrity of the human body that is closely related to chronological aging. A variety of biomarkers have been found to predict biological age. Biological age higher than chronological age (biological age acceleration) indicates an accelerated state of biological aging and a higher risk of premature morbidity and mortality. This study investigated how socioeconomic disadvantages influence biological aging. Methods The data from the National Health and Nutrition Examination Survey (NHANES) IV, including 10 nationally representative cross-sectional surveys between 1999-2018, were utilized. The analytic sample consisted of N = 48,348 individuals (20-84 years). We used a total of 11 biomarkers for estimating the biological age. Our main outcome was biological age acceleration, indexed by PhenoAge acceleration (PAA) and Klemera-Doubal biological age acceleration (KDM-A). Poverty was measured as a ratio of family income to the poverty thresholds defined by the U.S. Census Bureau, adjusted annually for inflation and family size (5 categories). The PAA and KDM-A were regressed on poverty levels, age, their interaction, education, sex, race, and a data collection wave. Sample weights were used to make the estimates representative of the U.S. adult population. Results The results showed that higher poverty was associated with accelerated biological aging (PAA: unstandardized coefficient B = 1.38 p |
Databáze: |
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