Is There any Alteration in Erythrocyte Folate Status in Patients with Thyroid and Breast Cancers?

Autor: Baydar Terken, Sahin Tevfik Tolga, Girgin Gozde, Sipahi Hande, Yuksel Osman, Taneri Ferit, Tekin Ercument
Jazyk: angličtina
Rok vydání: 2010
Předmět:
Zdroj: Pteridines, Vol 21, Iss 1, Pp 17-21 (2010)
Druh dokumentu: article
ISSN: 0933-4807
2195-4720
DOI: 10.1515/pteridines.2010.21.1.17
Popis: The aim of the study was to determine folate reserve in patients with thyroid and breast diseases. Erythrocyte folate concentrations of ninety-eight patients and thirty healthy subjects were determined by a modified microbiological assay. An increase in folate levels was observed in of both thyroid (n = 15) and breast (n = 22) cancer patients compared to controls, while a decrease was observed in benign breast disease patients (n = 24) compared to both control group and breast cancer patients. Patients with benign thyroid diseases (n = 37) had significantly lower folate concentrations as compared to both control and thyroid cancer groups. The results pointed out the elevated erythrocyte folate levels in the patients with malignant tumors.
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