Advances on association between indoor air pollution and 8-hydroxydeoxyguanosine in human urine

Autor: Jingang SHI, Miao HE
Jazyk: English<br />Chinese
Rok vydání: 2022
Předmět:
Zdroj: 环境与职业医学, Vol 39, Iss 4, Pp 465-469 (2022)
Druh dokumentu: article
ISSN: 2095-9982
DOI: 10.11836/JEOM21315
Popis: 8-hydroxydeoxyguanosine (8-OHdG) in human urine is a marker reflecting oxidative stress and DNA oxidative damage. People spend 80%-90% of their life indoors; therefore, indoor air quality is directly related to human health. In this paper, the urinary 8-OHdG levels were presented in populations grouped by different demographic characteristics, lifestyle, occupational exposure, and health status, and elucidated indoor pollutants affecting human urinary 8-OHdG level, such as pollutants from outdoor sources, smoking, indoor combustion and cooking fumes, the chemicals in interior decoration materials, and building foundation soils. The article aims to provide a theoretical basis for predicting the impact of indoor air pollution on human health (DNA oxidative damage and related diseases) by measuring the concentration of 8-OHdG in human urine.
Databáze: Directory of Open Access Journals