| Autor: |
G. A. Stamatiades, P. D’Silva, M. Elahee, G. M. Viana, A. Sideri-Gugger, S. K. Majumdar |
| Jazyk: |
angličtina |
| Rok vydání: |
2023 |
| Předmět: |
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| Zdroj: |
International Journal of Endocrinology, Vol 2023 (2023) |
| Druh dokumentu: |
article |
| ISSN: |
1687-8345 |
| DOI: |
10.1155/2023/6615624 |
| Popis: |
Context. Numerous reports suggest an association between SGLT2 inhibitors and DKA. Since the use of these drugs for diabetes has increased dramatically, identification of patients at greatest risk of this life-threatening complication is essential. Objective. To describe the clinical and biochemical characteristics of all reported cases of DKA associated with SGLT2 inhibitor use in patients with type 2 diabetes mellitus and to identify potential risk factors. Design. A retrospective case series was conducted between March 2013 and August 2019 using an electronic medical record search algorithm. Results. 25 patients met the criteria for DKA associated with SGLT2i use (total of 29 cases), 15 were female, average age was 54.24 years, and mean diabetes duration was 8.76 years. The majority of the patients (23 patients) had no history of prior DKA. Average blood glucose concentrations at presentation were 298.9 ± 152.7 mg/dl. Interestingly, nearly half of the episodes (14) met the criteria of euglycemic DKA (glucose |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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