| Autor: |
张帅，王润榕，侯红玲，任彬彬，刘振生，王苇，陈斌，张新江 |
| Jazyk: |
čínština |
| Rok vydání: |
2018 |
| Předmět: |
|
| Zdroj: |
Zhongguo cuzhong zazhi, Vol 13, Iss 4, Pp 322-326 (2018) |
| Druh dokumentu: |
article |
| ISSN: |
1673-5765 |
| DOI: |
10.3969/j.issn.1673-5765.2018.04.006 |
| Popis: |
目的 探讨应用支架样取栓装置对前循环大动脉闭塞所致急性缺血性卒中患者机械取栓治疗的临 床效果。 方法 连续纳入采用支架样取栓装置治疗的前循环急性颅内大动脉近端闭塞患者。分析纳入患 者的临床特征、影像学资料、治疗及术后90 d临床随访结果。以术后90 d改良Rankin量表（modified Rankin Scale，mRS）评分为主要指标评估治疗有效性，以症状性颅内出血率、术后90 d死亡率评估治疗 的安全性。 结果 共纳入30例患者，29例应用Solitaire，1例应用Trevo。平均年龄（65.97±11.67）岁。入院时美国 国立卫生研究院卒中量表(National Institutes of Health Stroke Scale，NIHSS)评分中位数13.50（9.75， 18.00）。包括颈内动脉闭塞9例，大脑中动脉M1段闭塞20例，大脑前动脉A1段闭塞1例。术后90 d随访， 56.7%（17/30）患者预后良好（mRS评分0～2分）。术后发生症状性颅内出血率13.3%（4/30），术后 90 d死亡率20%（6/30）。 结论 支架样取栓装置在前循环大动脉闭塞性急性缺血性卒中取栓治疗中临床效果较好，其有效 性、安全性能够在真实世界中得到体现，是治疗急性颅内大动脉闭塞的有效方法。 Abstract: Objective To investigate the clinical effect of stent-like retrievers for mechanical thrombectomy in ischemic stroke patients due to large vessel occlusion. Methods Patients treated with stent-like retrievers for mechanical thrombectomy caused by proximal arterial occlusion in anterior cerebral circulation were enrolled consecutively. Their clinical features, imaging data, treatments and the results of 90-day follow up were analyzed. The major efficacy measure was assessed with modified Rankin Scale (mRS) at 90 days after onset. The safety measures were assessed with symptomatic intracranial hemorrhage (sICH) and mortality at 90 days. Results Of the 30 enrolled patients, 29 were treated with Solitaire and 1 with Trevo. The mean age was (65.97±11.67) years old, and median baseline National Institutes of Health Stroke Scale (NIHSS) score was 13.50 (9.75, 18.00). Nine of them had internal carotid artery occlusion, 20 had the M1 segment of the middle cerebral artery occlusion and 1 had the A1 segment of the anterior cerebral artery occlusion. The proportion of favorable functional outcome (mRS 0-2 at 90 days) was 56.7% (17/30). sICH rate was 13.3% (4/30), and the mortality at 90 days was 20% (6/30). Conclusion The effect of stent-like retrievers for mechanical thrombectomy in ischemic stroke patients due to anterior cerebral circulation large vessel occlusion is relatively good. Its efficacy and safety can be reflected in the real world, and it is an effective method for the treatment of acute intracranial artery occlusion. |
| Databáze: |
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