Influence of albuminuria and glomerular filtration rate on blood pressure response to antihypertensive drug therapy

Autor: John M Flack, Karl Duncan, Suzanne E Ohmit, Ruth Quah, Xuefeng Liu, et al
Jazyk: angličtina
Rok vydání: 2008
Předmět:
Zdroj: Vascular Health and Risk Management, Vol Volume 3, Pp 1029-1037 (2008)
Druh dokumentu: article
ISSN: 1178-2048
Popis: John M Flack1, Karl Duncan2, Suzanne E Ohmit3, Ruth Quah1, Xuefeng Liu1, Preeti Ramappa1, Sandra Norris1, Lowell Hedquist1, Amanda Dudley1, Samar A Nasser11Division of Translational Research and Clinical Epidemiology, Department of Internal Medicine, Wayne State University, Detroit, MI, USA; 2Department of Interventional Cardiology, Harper University Hospital, Detroit Medical Center, Detroit, MI, USA; 3School of Public Health, University of Michigan, Ann Arbor, MI, USABackground: Albuminuria and glomerular filtration rate (GFR), two factors linked to kidney and vascular function, may influence longitudinal blood pressure (BP) responses to complex antihypertensive drug regimens.Methods: We reviewed the clinic records of 459 patients with hypertension in an urban, academic practice.Results: Mean patient age was 57-years, 89% of patients were African American, and 69% were women. Mean patient systolic/diastolic BP (SBP/DBP) at baseline was 171/98 mmHg while taking an average of 3.3 antihypertensive medications. At baseline, 27% of patients had estimated (e)GFR
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