The secular trend of enterovirus A71 after the implementation of preventive measures in Taiwan

Autor: Ya-Li Hu, Chiu-Mei Chen, En-Tzu Wang, Hung-Wei Kuo, Wei-Liang Shih, Chi-Tai Fang, Ding-Ping Liu, Luan-Yin Chang
Jazyk: angličtina
Rok vydání: 2022
Předmět:
Zdroj: BMC Public Health, Vol 22, Iss 1, Pp 1-9 (2022)
Druh dokumentu: article
ISSN: 1471-2458
DOI: 10.1186/s12889-022-13916-0
Popis: Abstract Background Enterovirus A71 (EV A71) is one of the most important enteroviruses related to morbidity and mortality in children worldwide. This study aimed to analyse the secular trend of EV A71 in Taiwan from 1998 to 2020 and to evaluate the effectiveness of infection control measures. Methods We collected the epidemiological data of EV A71 from disease surveillance systems in Taiwan. We analysed the association between the secular trend of EV A71 and preventive measures such as hand washing, case isolation, and suspension of classes. Results The incidence of enterovirus infections with severe complications (EVSC) decreased from 16.25 per 100,000 children under six in 1998 to less than 9.73 per 100,000 children under six after 2012 (P = 0.0022). The mortality rate also decreased significantly, from 3.52 per 100,000 children under six in 1998 to 0 per 100,000 children under six in 2020 (P
Databáze: Directory of Open Access Journals
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